4-Chloro-1H-pyrazolo[3,4-b]pyridine
4-Chloro-1H-pyrazolo[3,4-b]pyridine
CAS: 29274-28-0
Molecular Formula: C6H4ClN3
4-Chloro-1H-pyrazolo[3,4-b]pyridine - Names and Identifiers
4-Chloro-1H-pyrazolo[3,4-b]pyridine - Physico-chemical Properties
| Molecular Formula | C6H4ClN3 |
| Molar Mass | 153.57 |
| Density | 1.61±0.1 g/cm3(Predicted) |
| Boling Point | 194.5±50.0 °C(Predicted) |
| Flash Point | 169°C |
| Vapor Presure | 0.00126mmHg at 25°C |
| Appearance | Solid |
| pKa | 4.56±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.72 |
4-Chloro-1H-pyrazolo[3,4-b]pyridine - Introduction
4-Chloro-1H-pyrazolo[3,4-b]pyridine(4-Chloro-1H-pyrazolo[3,4-b]pyridine) is an organic compound with the chemical formula C8H5ClN2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystalline solid;
-Melting point: About 115-119 ° C;
-Boiling point: About 350 ° C;
-Density: about 1.314 g/cm ^ 3.
Use:
- 4-Chloro-1H-pyrazolo[3,4-b]pyridine can be used as an intermediate in organic synthesis, and has a wide range of applications in drug synthesis and pesticide synthesis.
Method:
- 4-Chloro-1H-pyrazolo[3,4-b]pyridine can be prepared from the reaction of 3-fluoro-4-nitropyridine and bromoacetate, and then through quaternary ammonium salt reduction, oxidation reaction, the elimination reaction and further reaction and purification steps give the desired product.
Safety Information:
- 4-Chloro-1H-pyrazolo[3,4-b]pyridine needs to pay attention to the safety measures of fire prevention and static electricity accumulation when using and storing;
-The compound may be irritating to the eyes, skin and respiratory system, and appropriate personal protective equipment is required when exposed;
-When used in laboratory and industrial settings, it is necessary to follow safe operating procedures and establish appropriate protective measures, including a well-ventilated work environment and the use of personal protective equipment.
Please note that the information provided above is for reference only. Specific chemical experiments or applications need to be judged and processed according to actual conditions.
Nature:
-Appearance: Colorless to light yellow crystalline solid;
-Melting point: About 115-119 ° C;
-Boiling point: About 350 ° C;
-Density: about 1.314 g/cm ^ 3.
Use:
- 4-Chloro-1H-pyrazolo[3,4-b]pyridine can be used as an intermediate in organic synthesis, and has a wide range of applications in drug synthesis and pesticide synthesis.
Method:
- 4-Chloro-1H-pyrazolo[3,4-b]pyridine can be prepared from the reaction of 3-fluoro-4-nitropyridine and bromoacetate, and then through quaternary ammonium salt reduction, oxidation reaction, the elimination reaction and further reaction and purification steps give the desired product.
Safety Information:
- 4-Chloro-1H-pyrazolo[3,4-b]pyridine needs to pay attention to the safety measures of fire prevention and static electricity accumulation when using and storing;
-The compound may be irritating to the eyes, skin and respiratory system, and appropriate personal protective equipment is required when exposed;
-When used in laboratory and industrial settings, it is necessary to follow safe operating procedures and establish appropriate protective measures, including a well-ventilated work environment and the use of personal protective equipment.
Please note that the information provided above is for reference only. Specific chemical experiments or applications need to be judged and processed according to actual conditions.
Last Update：2024-04-09 19:05:48
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View History
4-Chloro-1H-pyrazolo[3,4-b]pyridine
2,6-difluorobenzyl
N-(2-Chloro-2-oxoethyl)phthalimide
3-chloro-4-[(3-fluorophenyl)Methoxy]aniline
ETHYL (3,4-DICHLOROBENZOYL)ACETATE
3-正-丙基茚苯酞,(E)+(Z)
甲基锂
N-alpha-Trifluoracetyl-glycin
2-CHLORO-3-FLUORO-4-IODOPYRIDINE
1,2-didecanoylglycerol
2,6-difluorobenzyl
N-(2-Chloro-2-oxoethyl)phthalimide
3-chloro-4-[(3-fluorophenyl)Methoxy]aniline
ETHYL (3,4-DICHLOROBENZOYL)ACETATE
3-正-丙基茚苯酞,(E)+(Z)
甲基锂
N-alpha-Trifluoracetyl-glycin
2-CHLORO-3-FLUORO-4-IODOPYRIDINE
1,2-didecanoylglycerol